It is certified as 100% blue weber agave tequila. DeLeón is produced in the town of Purísima del Rincón in the Mexican state of Guanajuato. The city name literally translates to "Purest of the Corner" and the town is named after the Immaculate Conception.

DeLeón Tequila was founded and created by Brent Hocking in 2008. It was first introduced to the US market on Cinco de Mayo, 2009. DeLeón Tequila does not use any of the four allowable chemicals permitted by the CRT (Consejo Regulador Del Tequila). Glycerin, sucrose, oak extract and caramel are not added to DeLeón Tequila. In December 2013 it was announced that Sean Combs would become a partner of DeLeón tequila following the success of his work with Cîroc Vodka. A few weeks later it emerged that Sean Combs had in fact bought DeLeón Tequila in partnership with Diageo, with whom he had worked with on growing Cîroc. Following the purchase Diageo and Sean Combs each own 50% of DeLeón Tequila.